Malignant Hyperthermia - 10
The Malignant Hyperthermia Susceptible (MHS) Patient
A simple three-step safe plan is suggested:

MHS Safe Plan
Be prepared to treat a full blown episode. Have dantrolene available. Safe agents include thiopental, propofol, ketamine, narcotics, benzodiazepines, nondepolarizing muscle relaxants.
Yes, even outpatient surgery is acceptable, though some would extend the postoperative monitoring period to 2 to 4 hours.

Myopathies Associated with Malignant Hyperthermia
Two myopathies are clearly associated with MH:
central core disease (CCD) and
multiminicore disease (MmD).
Patients with these myopathies should be treated as malignant hyperthermia susceptible.



Greg Gordon MD
Updated: