Ketamine - 1

Ketamine, a phencyclidine derivative, is arguably our most ideal anesthetic agent!

History
1958: phencyclidine (phenyl cyclohexyl piperidine, PCP) introduced into clinical anesthesia *

1959: cyclohexamine tried *


1962: ketamine (Ketalar) synthesized by Stevens

1965: ketamine tried in humans *


1970: ketamine officially released for clinical use in U.S.

1999: ketamine becomes a schedule III substance under the CSA
