Etomidate - 3
Metabolism
In the liver:
![]() etomidate |
---> ester hydrolysis (MAJOR) |
![]() carboxylic acid of etomidate |
---> N-dealkylation (minor) |
![]() ethyl-imidazole-5-carbolylate |

The major metabolite, the carboxylic acid of etomidate, is inactive. Etomidate metabolites are excreted in the urine (85%) and bile (15%).
